Prescient Lab Services

LifeKit® PreScript

State-of-the-art pharmacogenomics testing

No medicine works the same for everyone. Results can vary widely because a person’s genetics impact how their body metabolizes different medications. Response rates for many drugs are only 50-75%.1

Instead of going through the painstaking process of trial and error with new medications, which can be expensive, time-consuming, and frustrating, LifeKit PreScript is a genetic test that helps providers identify which medications are most likely to be effective and which should be avoided based on their patients’ DNA. Research has shown that >90% of patients possess clinically actionable genetic variants that affect their drug response.2,3

Using a simple cheek swab sample, LifeKit PreScript analyzes 14 genetic variants that impact how a person’s body metabolizes medication. Providers receive a detailed report that indicates how an individual will respond to the medications they are currently prescribed, as well as any medications being considered for future use, to help support more informed decision-making about drug selection.

1 Spear BB, Heath-Chiozzi M, Hu J: Clinical application of pharmacogenetics. Trends Mol. Med.7, 201–204 (2001).
2 Van Driest, SL, et. al., Clin Pharmacol Ther. 2014; 95(4): 423–431.
3 Yuan, J. et. al., Jmol Diag. 2016; 18(3): 438-445.

Genetic Variants Analyzed by LifeKit PreScript:

CYP2D6
CYP2C9
CYP2C19
CYP1A2
CYPA3A4
CYP3A5
SLC6A4
OPRM1
VKORC1
SLC01B1
Factor II
Factor V (Leiden)
MTHFR
COMT